Alvum Smart Patch for Predicting IBD Flare-Ups Before Symptoms Start

Inflammatory Bowel Disease (IBD) causes unpredictable flare-ups that interfere with daily life, often without warning. For people living with Crohn’s disease or ulcerative colitis, the fear of the next episode can be overwhelming. Alvum offers a discreet, wearable patch that provides early alerts before symptoms begin—giving users time to act and manage their condition with confidence.

This smart device analyzes biomarkers in sweat to predict flare-ups well in advance. With a comfortable fit, multi-signal alerts, and a month-long battery life, Alvum brings peace of mind to IBD patients every day.

How Alvum Predicts Flare-Ups Using Sweat Biomarkers

Alvum’s technology is based on continuous monitoring of eccrine sweat, which the body produces naturally throughout the day. The device attaches to the user’s arm using a soft adhesive and collects sweat through a disposable sensor cartridge. Inside this cartridge, antibodies bind to specific interleukin markers—IL-1α for Crohn’s disease and IL-1β for ulcerative colitis.

When inflammation begins to rise, these biomarkers increase. The binding reaction changes the conductivity of the cartridge’s chemical strip, which is detected by internal electrodes. Once a flare-up is detected, the processor activates a 3-in-1 alert: vibration, blinking LED, and sound. This allows the user to prepare for symptoms even before they feel unwell.

Comfortable, Reliable, and Built for Daily Life

Alvum is designed to be worn at all times. It’s lightweight, compact, and can be worn discreetly under clothing. The patch is comfortable enough for continuous use and remains in place throughout normal activities, including walking, sitting, or sleeping.

The internal battery lasts over a month without charging. Users only need to replace the cartridge when required, making daily operation simple. The multi-signal alert system ensures the user won’t miss a notification, whether at home or outside.

Cartridges are tailored to specific conditions and are available by one-time purchase or subscription. This supports long-term, uninterrupted use.

Personalized Monitoring for Crohn’s and Colitis Patients

Alvum is unique in offering separate cartridges for Crohn’s disease and ulcerative colitis. Each one uses specialized antibodies to detect the specific interleukin relevant to the patient’s condition. This precise targeting enhances accuracy and minimizes false alarms.

By identifying inflammation at an early stage, Alvum gives patients and healthcare providers a chance to respond proactively—whether that means adjusting medication, modifying diet, or planning ahead to avoid stress and physical strain.

This personalized approach helps reduce the frequency and severity of flare-ups while improving quality of life.

Living With Confidence Thanks to Alvum

Alvum is more than just a patch—it’s a tool that restores a sense of control for people living with IBD. Instead of being caught off guard by sudden symptoms, users can make informed decisions about their care in advance.

With early detection, continuous protection, and effortless integration into daily life, Alvum supports people in leading a fuller, more predictable life, free from constant worry about the next relapse.